Fig. 1 · Structure
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VQW-765
α7-nAChR Agonist
VQW-765 is a selective agonist for the alpha-7 nicotinic acetylcholine receptor (α7-nAChR), exhibiting a pKD value of 7.56 in recombinant human α7-nAChR assays. This compound demonstrates anxiolytic-like effects in vivo, making it a valuable tool for the study of anxiety disorders and acute performance anxiety. Researchers can utilize VQW-765 to investigate the role of α7-nAChR modulation in neuropsychiatric conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 669770-29-0 |
| Applications | α7-nAChR Agonist |
| Formula | C19H22N2O |
| Molecular Weight | 294.39 |
| Synonyms | AQW-051 |
| SMILES | CC1=CC=C(C2=CC=C(O[C@H]3CN4CCC3CC4)C=N2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.