Fig. 1 · Structure
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VU 0360223
mGluR Allosteric Modulator
VU 0360223 is a potent negative allosteric modulator of metabotropic glutamate receptors (mGluR) with an IC50 of 61 nM. This compound is useful for studying the modulation of glutamatergic signaling pathways and has potential applications in neuropharmacology and psychiatric research. Its ability to selectively inhibit mGluR may contribute to the understanding of various neurological disorders, making it a valuable tool in chemical biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1274859-33-4 |
| Applications | mGluR Allosteric Modulator |
| Formula | C15H9FN2S |
| Molecular Weight | 268.31 |
| SMILES | N#CC1=CC(C2=CC=C(SC(C)=N3)C3=C2)=CC(F)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.