VU-1545 is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5) with a Ki of 156 nM and an EC50 of 9.6 nM. This compound enhances mGluR5 activity, offering potential insights into synaptic transmission and plasticity. VU-1545 is valuable in research focused on neurological disorders, cognition, and mood regulation, making it a useful tool for studying the role of mGluR5 in various pathological conditions.
VU-1545 is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5) with a Ki of 156 nM and an EC50 of 9.6 nM. This compound enhances mGluR5 activity, offering potential insights into synaptic transmission and plasticity. VU-1545 is valuable in research focused on neurological disorders, cognition, and mood regulation, making it a useful tool for studying the role of mGluR5 in various pathological conditions.
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