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VU0080241

Catalog No.: A61811
mGluR4 PAM
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), exhibiting an EC50 of 4.6 μM. This compound enhances mGluR4 receptor activity, making it a valuable tool for studying glutamatergic signaling. VU0080241 holds potential applications in neurological research and may contribute to the development of therapies for conditions involving glutamate dysregulation.
VU0080241 393845-24-4 mGluR4 PAM
Grouped product items
Size Price Stock Qty
10mg
$25.00
In stock
25mg
$55.00
In stock
50mg
$90.00
In stock
100mg
$145.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), exhibiting an EC50 of 4.6 μM. This compound enhances mGluR4 receptor activity, making it a valuable tool for studying glutamatergic signaling. VU0080241 holds potential applications in neurological research and may contribute to the development of therapies for conditions involving glutamate dysregulation.
Product Information
Catalog NumA61811
FormulaC19H23N5
Molecular Weight321.42
CAS Number393845-24-4
SMILESCC1CN(CCC1)C2=C3C(N(N=C3)C4=CC=C(C=C4C)C)=NC=N2
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GPCR/G Protein > Metabotropic glutamate receptors (mGluR)