Fig. 1 · Structure
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VU0080241
mGluR4 PAM
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), exhibiting an EC50 of 4.6 μM. This compound enhances mGluR4 receptor activity, making it a valuable tool for studying glutamatergic signaling. VU0080241 holds potential applications in neurological research and may contribute to the development of therapies for conditions involving glutamate dysregulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 393845-24-4 |
| Applications | mGluR4 PAM |
| Formula | C19H23N5 |
| Molecular Weight | 321.42 |
| SMILES | CC1CN(CCC1)C2=C3C(N(N=C3)C4=CC=C(C=C4C)C)=NC=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.