Fig. 1 · Structure
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VU0155041 sodium
mGluR4 Allosteric Agonist
VU0155041 sodium is a potent, selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4). With EC50 values of 798 nM and 693 nM for human and rat mGluR4, respectively, this compound is instrumental in enhancing receptor activity. VU0155041 sodium shows promise in the study of Parkinson's disease, providing a valuable tool for understanding its pathophysiology and developing potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1259372-69-4 |
| Applications | mGluR4 Allosteric Agonist |
| Formula | C14H14Cl2NNaO3 |
| Molecular Weight | 338.16 |
| SMILES | O=C([C@H](CCCC1)[C@H]1C(O[Na])=O)NC2=CC(Cl)=CC(Cl)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.