VU0240382 is a modulator of metabotropic glutamate receptor subtype 5 (mGluR5), exhibiting dual mechanisms governed by its allosteric agonist activity. When functioning as an allosteric agonist, VU0240382 effectively activates mGluR5 receptors in cell line studies; however, it does not demonstrate agonist activity in natural biological systems. Its efficacy parallels that of mGluR5 modulators lacking allosteric agonist properties in animal models, making it a valuable tool for researching psychiatric disorders and neurological diseases where mGluR5 is implicated.
VU0240382 is a modulator of metabotropic glutamate receptor subtype 5 (mGluR5), exhibiting dual mechanisms governed by its allosteric agonist activity. When functioning as an allosteric agonist, VU0240382 effectively activates mGluR5 receptors in cell line studies; however, it does not demonstrate agonist activity in natural biological systems. Its efficacy parallels that of mGluR5 modulators lacking allosteric agonist properties in animal models, making it a valuable tool for researching psychiatric disorders and neurological diseases where mGluR5 is implicated.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
