Fig. 1 · Structure
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VU0359516
VU0359516 is a selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4). This compound enhances mGluR4 activity, exhibiting improved potency and efficacy compared to earlier modulators. VU0359516 is valuable for research exploring the role of mGluR4 in neurological disorders and may contribute to therapeutic strategies targeting excitatory neurotransmission.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1220513-59-6 |
| Formula | C16H13N3O3 |
| Molecular Weight | 295.29 |
| SMILES | O=C(NC1=NC=CC=C1)C2(OC3=CC=CC=C3/4)CC2C4=N/O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.