Fig. 1 · Structure
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VU0361747
mGluR4 PAM
VU0361747 is a selective positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4 PAM). This compound exhibits neuroprotective effects and has been shown to significantly reverse amphetamine-induced hyperlocomotion in vivo. It is a valuable tool for research into neuropharmacology and the modulation of glutamatergic signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1309976-66-6 |
| Applications | mGluR4 PAM |
| Formula | C19H17FN2O2 |
| Molecular Weight | 324.35 |
| SMILES | OC1CCN(CC1)C(C2=CC=C(N=C2)C#CC3=CC=CC(F)=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.