Fig. 1 · Structure
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VU0400195
Metabotropic Gutamate Receptor 4 Modulator
VU0400195 is an allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4) with an EC50 of 291 nM. This compound exhibits potential antiparkinsonian activity and is valuable for research involving animal models of Parkinson's disease. Its specificity for mGlu4 may provide insights into therapeutic strategies for neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1309434-83-0 |
| Applications | Metabotropic Gutamate Receptor 4 Modulator |
| Formula | C21H16ClN3O3 |
| Molecular Weight | 393.82 |
| Synonyms | ML182 |
| SMILES | O=C(C1=NC=CC=C1)NC2=CC=C(C(Cl)=C2)N3C([C@@]4([C@@]5([H])C[C@@]([H])([C@]4([H])C3=O)C=C5)[H])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.