Fig. 1 · Structure
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VU0420373
HssRS Activator
VU0420373 is a potent activator of the heme sensor system (HssRS), exhibiting an EC50 of 10.7 μM and a pEC50 of 4.97. This compound stimulates heme biosynthesis and demonstrates toxicity towards fermenting Staphylococcus aureus. VU0420373 is valuable for research applications exploring heme regulation and the physiological roles of heme in bacterial systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 38376-29-3 |
| Applications | HssRS Activator |
| Formula | C15H11FN2O |
| Molecular Weight | 254.26 |
| SMILES | OC1=CC=CC=C1C2=NNC(C3=CC=CC=C3F)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.