Fig. 1 · Structure
Documents & Downloads
VU0431316
mGlu5 Antagonist
VU0431316 is a potent non-competitive antagonist of the metabotropic glutamate receptor 5 (mGlu5), exhibiting an IC50 value of 24 nM. This compound selectively inhibits mGlu5 signaling pathways, making it a valuable tool for research into glutamate-mediated neurological disorders. Its use in various preclinical studies may enhance the understanding of mGlu5 receptor functions and their role in neurobiology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1620203-63-5 |
| Applications | mGlu5 Antagonist |
| Formula | C14H9ClN6O2 |
| Molecular Weight | 328.71 |
| SMILES | O=C(C1=NC=CC(Cl)=C1)NC2=NC(OC3=CN=CN=C3)=CN=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.