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VU0519975

Raft Destabilizing Compound

VU0519975 is a raft destabilizing compound that targets lipid raft microdomains within cellular membranes. This compound effectively reduces the partitioning of PMP22 in lipid rafts, leading to the destabilization of ordered domains. VU0519975 serves as a valuable tool in research applications focused on membrane biophysics and the study of phase separation in cellular processes, particularly in the context of glycerophospholipid membrane vesicles (GPMVs).

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1211788-57-6
Applications	Raft Destabilizing Compound
Formula	C₁₇H₁₇ClN₄OS₂
Molecular Weight	392.93
SMILES	O=C(NC1=CC=CS1)N(CC2)CCN2C3=NC4=C(C(Cl)=CC=C4C)S3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.