VU0631019 is a selective antagonist of the serotonin receptor 5-HT2B, exhibiting an IC50 value of 29 nM. This compound is useful in studying the role of 5-HT2B in various physiological processes and disease states. Due to its predicted limited ability to penetrate the blood-brain barrier and potential for P-glycoprotein-mediated efflux, VU0631019 can be utilized in in vitro and ex vivo experimental settings to explore peripheral effects of 5-HT2B modulation.
VU0631019 is a selective antagonist of the serotonin receptor 5-HT2B, exhibiting an IC50 value of 29 nM. This compound is useful in studying the role of 5-HT2B in various physiological processes and disease states. Due to its predicted limited ability to penetrate the blood-brain barrier and potential for P-glycoprotein-mediated efflux, VU0631019 can be utilized in in vitro and ex vivo experimental settings to explore peripheral effects of 5-HT2B modulation.
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