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VU0652925

Catalog No.: A63507
PAR4 Antagonist
VU0652925 is a potent PAR4 antagonist, demonstrating IC50 values of 43 pM and 39.2 pM for PAC1 and P-selectin, respectively. This compound effectively inhibits GPIIbIIIa activation, making it a valuable tool for investigating the role of PAR4 in platelet activation and related cardiovascular research applications.
VU0652925 1476847-58-1 PAR4 Antagonist
Grouped product items
Size Price Stock Qty
25mg
$2,410.00
In stock
50mg
$3,100.00
In stock
100mg
$4,160.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVU0652925 is a potent PAR4 antagonist, demonstrating IC50 values of 43 pM and 39.2 pM for PAC1 and P-selectin, respectively. This compound effectively inhibits GPIIbIIIa activation, making it a valuable tool for investigating the role of PAR4 in platelet activation and related cardiovascular research applications.
Product Information
Catalog NumA63507
FormulaC24H18N4O4S2
Molecular Weight490.55
CAS Number1476847-58-1
SMILESCOC1=NN2C(S1)=NC(C3=CC4=C(C=C(C=C4OCC5=CSC(C6=CC=CC=C6)=N5)OC)O3)=C2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Protease-Activated Receptors (PAR)