Documents & Downloads

VU6001192

mGlu2 Negative Allosteric Modulator

VU6001192 is a selective negative allosteric modulator of the metabotropic glutamate receptor 2 (mGlu2). Demonstrating potent inhibitory activity with an IC50 of 207 nM, VU6001192 does not affect the mGlu3 receptor or other mGlu receptor subtypes. This compound is valuable for research into neurological disorders, particularly in the context of depression.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	1821325-29-4
Applications	mGlu2 Negative Allosteric Modulator
Formula	C₂₃H₂₄FN₃O₃
Molecular Weight	409.45
SMILES	O=C1C(C(N)=O)=CN(C2=CC=C(CN3C[C@H](O[C@H](C3)C)C)C=C21)C4=CC=C(C=C4)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.