Fig. 1 · Structure
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VU6010572
mGlu3 Negative Allosteric Modulator
VU6010572 is a potent and selective negative allosteric modulator of the metabotropic glutamate receptor 3 (mGlu3), demonstrating an IC50 of 245 nM. Its high blood-brain barrier penetration makes it suitable for central nervous system studies. This compound is valuable in investigating the role of mGlu3 in neuropsychiatric disorders and evaluating potential therapeutic strategies in related research contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2126784-39-0 |
| Applications | mGlu3 Negative Allosteric Modulator |
| Formula | C20H18FNO3 |
| Molecular Weight | 339.36 |
| SMILES | O=C1C=C(OC[C@@H](OC2=CC=CC=C2)C)C=CN1C3=CC=C(F)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.