VU6015929 is a potent and selective dual inhibitor of discoidin domain receptors 1 and 2 (DDR1/2), exhibiting IC50 values of 4.67 nM and 7.39 nM, respectively. This compound effectively inhibits collagen-induced activation of DDR1 and reduces collagen-IV production, making it a valuable tool for research on fibrosis and extracellular matrix remodeling. VU6015929 is suitable for studying the roles of DDR1/2 in various pathological processes and therapeutic interventions.
VU6015929 is a potent and selective dual inhibitor of discoidin domain receptors 1 and 2 (DDR1/2), exhibiting IC50 values of 4.67 nM and 7.39 nM, respectively. This compound effectively inhibits collagen-induced activation of DDR1 and reduces collagen-IV production, making it a valuable tool for research on fibrosis and extracellular matrix remodeling. VU6015929 is suitable for studying the roles of DDR1/2 in various pathological processes and therapeutic interventions.
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