VU6043653 is a potent negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5), exhibiting an IC50 value of 325 nM for human mGlu5. This compound selectively influences mGlu5 signaling pathways, making it a valuable tool for studying neuropharmacology and neurodegenerative diseases. Its ability to cross the blood-brain barrier enhances its utility in in vivo research applications focused on central nervous system disorders.
VU6043653 is a potent negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5), exhibiting an IC50 value of 325 nM for human mGlu5. This compound selectively influences mGlu5 signaling pathways, making it a valuable tool for studying neuropharmacology and neurodegenerative diseases. Its ability to cross the blood-brain barrier enhances its utility in in vivo research applications focused on central nervous system disorders.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
