Fig. 1 · Structure
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VUF10497
H4R Inverse Agonist
VUF10497 is a potent inverse agonist of the histamine H4 receptor (H4R). It demonstrates significant anti-inflammatory activity, making it a valuable tool for research focused on inflammation and immune response modulation. This compound can be utilized in studies examining the role of H4R in various inflammatory conditions and may aid in the development of new therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 1080623-12-6 |
| Applications | H4R Inverse Agonist |
| Formula | C18H20ClN5S |
| Molecular Weight | 373.90 |
| SMILES | CN1CCN(CC1)C2=NC(NCC3=CC=CS3)=C4C=C(C=CC4=N2)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.