Vulolisib is a potent, orally active inhibitor of phosphatidylinositol 3-kinase (PI3K), demonstrating IC50 values of 0.2 nM for PI3Kα, 168 nM for PI3Kβ, 90 nM for PI3Kγ, and 49 nM for PI3Kδ. This compound exhibits significant antiproliferative and antineoplastic properties, making it a valuable tool for cancer research. Its selective inhibition of PI3K isoforms facilitates investigations into the role of PI3K signaling in various malignancies.
Vulolisib is a potent, orally active inhibitor of phosphatidylinositol 3-kinase (PI3K), demonstrating IC50 values of 0.2 nM for PI3Kα, 168 nM for PI3Kβ, 90 nM for PI3Kγ, and 49 nM for PI3Kδ. This compound exhibits significant antiproliferative and antineoplastic properties, making it a valuable tool for cancer research. Its selective inhibition of PI3K isoforms facilitates investigations into the role of PI3K signaling in various malignancies.
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