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Vupanorsen

ANGPTL Inhibitor

Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that specifically targets and inhibits the synthesis of Angiopoietin-like 3 (ANGPTL3). This compound is demonstrated to effectively lower triglyceride levels and reduce atherogenic lipoprotein concentrations. Its primary applications include research on lipid metabolism, cardiovascular disease, and the therapeutic potential for dyslipidemia management.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2097587-62-5
Applications	ANGPTL Inhibitor
Synonyms	IONIS ANGPT-L3Rx; ISIS 703802

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.