VX-984 is a potent and selective DNA-PK inhibitor that effectively penetrates the blood-brain barrier. It disrupts the non-homologous end joining (NHEJ) repair pathway, leading to an increase in DNA double-strand breaks (DSBs). This compound has significant research applications in the study of glioblastomas (GBM) and non-small cell lung cancer (NSCLC). Ideal for investigations into cancer therapy and DNA damage response mechanisms.
VX-984 is a potent and selective DNA-PK inhibitor that effectively penetrates the blood-brain barrier. It disrupts the non-homologous end joining (NHEJ) repair pathway, leading to an increase in DNA double-strand breaks (DSBs). This compound has significant research applications in the study of glioblastomas (GBM) and non-small cell lung cancer (NSCLC). Ideal for investigations into cancer therapy and DNA damage response mechanisms.
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