Fig. 1 · Structure
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WAY-100135 dihydrochloride
5-HT1A Antagonist
WAY-100135 dihydrochloride is a selective antagonist of the 5-HT1A receptor, exhibiting an IC50 value of 34 nM in the rat hippocampal model. This compound is of significant interest for research into its potential antipsychotic properties and its role in neurological studies. The inhibition of both presynaptic and postsynaptic 5-HT1A receptors suggests its application in investigating serotonergic signaling and related pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 149055-79-8 |
| Applications | 5-HT1A Antagonist |
| Formula | C24H35Cl2N3O2 |
| Molecular Weight | 468.46 |
| SMILES | O=C(NC(C)(C)C)C(C1=CC=CC=C1)CN2CCN(C3=CC=CC=C3OC)CC2.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.