WAY-181187 hydrochloride is a potent and selective full agonist of the 5-HT6 receptor, exhibiting a Ki of 2.2 nM and an EC50 of 6.6 nM. This compound activates 5-HT6 receptor-dependent signaling pathways, including cAMP, Fyn, and ERK1/2 kinase, making it a valuable tool for research into neuropharmacology and the modulation of serotonergic pathways. Its selective action supports investigations into potential therapeutic applications for cognitive disorders and other conditions influenced by serotonin signaling.
WAY-181187 hydrochloride is a potent and selective full agonist of the 5-HT6 receptor, exhibiting a Ki of 2.2 nM and an EC50 of 6.6 nM. This compound activates 5-HT6 receptor-dependent signaling pathways, including cAMP, Fyn, and ERK1/2 kinase, making it a valuable tool for research into neuropharmacology and the modulation of serotonergic pathways. Its selective action supports investigations into potential therapeutic applications for cognitive disorders and other conditions influenced by serotonin signaling.
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