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WCK-5153

Penicillin-Binding Protein 2 Inhibitor

WCK-5153 is a selective inhibitor of Penicillin-Binding Protein 2 (PBP2), demonstrating an IC50 value of 0.14 μg/ml specifically for Pseudomonas aeruginosa PBP2. By enhancing the efficacy of β-lactam antibiotics, WCK-5153 serves as a valuable tool in the study of multidrug-resistant (MDR) pathogens. This compound is essential for research focused on overcoming antibiotic resistance and developing new therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1452460-79-5
Applications	Penicillin-Binding Protein 2 Inhibitor
Formula	C₁₂H₁₉N₅O₇S
Molecular Weight	377.37
SMILES	O=C([C@H]1CCNC1)NNC([C@H]2N(C(N3OS(=O)(O)=O)=O)C[C@H]3CC2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.