Fig. 1 · Structure
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WEHI-150
DNA Interstrand Crosslink Agent
WEHI-150 is a potent DNA interstrand crosslink agent that mimics the action of mitoxantrone. It effectively induces crosslinks between DNA strands, thereby disrupting replication and transcription processes. This compound is primarily used in cancer research to explore mechanisms of resistance and sensitivity to DNA-damaging agents, making it a valuable tool for studies on tumor biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 70492-21-6 |
| Applications | DNA Interstrand Crosslink Agent |
| Formula | C22H30N6O4 |
| Molecular Weight | 442.51 |
| SMILES | NCCNCCNC1=CC=C(C2=C1C(C3=C(C=CC(O)=C3C2=O)O)=O)NCCNCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.