WEHI-345

Catalog No.: A21012

RIPK2 inhibitor

WEHI-345

WEHI-345 Chemical Structure

CAS NO. 1354825-58-3

WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $108.00

Special Price $86.40

10 mg

Regular Price: $186.00

Special Price $148.80

50 mg

Regular Price: $552.00

Special Price $441.60

100 mg

Regular Price: $1,104.00

Special Price $883.20

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Biological Activity

WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.91 mL 124.55 mL 249.09 mL
0.5 mM 4.98 mL 24.91 mL 49.82 mL
1 mM 2.49 mL 12.45 mL 24.91 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21012
Actions Inhibitor
CAS No. 1354825-58-3
Formula C22H23N7O
M. Wt 401.46
Purity >98%
Synonyms WEHI345, WEHI 345
SMILES O=C(C1=CC=NC=C1)NCC(C)(N2N=C(C3=CC=C(C)C=C3)C4=C(N)N=CN=C42)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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