WEHI-345

Catalog No.: A21012

RIPK2 inhibitor

WEHI-345

WEHI-345 Chemical Structure

CAS NO. 1354825-58-3

WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation.

Availability: In stock

Package Price Qty
5 mg
$108.00
10 mg
$186.00
50 mg
$552.00
100 mg
$1,104.00
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Biological Activity

WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.91 mL 124.55 mL 249.09 mL
0.5 mM 4.98 mL 24.91 mL 49.82 mL
1 mM 2.49 mL 12.45 mL 24.91 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21012
Actions Inhibitor
M. Wt 401.46
Formula C22H23N7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1354825-58-3
Synonyms WEHI345, WEHI 345
SMILES O=C(C1=CC=NC=C1)NCC(C)(N2N=C(C3=CC=C(C)C=C3)C4=C(N)N=CN=C42)C

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