WEHI-539 hydrochloride

Catalog No.: A13327

Bcl-xL inhibitor

WEHI-539 hydrochloride

WEHI-539 hydrochloride Chemical Structure

CAS NO. Not avalable.

WEHI-539 hydrochloride is a small-molecule inhibitor of BCL-xL with IC50 value of 1.1 nM.

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Biological Activity

WEHI-539 hydrochloride is a small-molecule inhibitor of BCL-xL with IC50 value of 1.1 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.12 mL 80.62 mL 161.24 mL
0.5 mM 3.22 mL 16.12 mL 32.25 mL
1 mM 1.61 mL 8.06 mL 16.12 mL
5 mM 0.32 mL 1.61 mL 3.22 mL

*The above data is based on the productmolecular weight 620.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13327
Actions Inhibitor
CAS No. Not avalable.
Formula C31H30ClN5O3S2
M. Wt 620.18
Solubility DMSO
Purity >98%
Synonyms WEHI539 hydrochloride, WEHI 539 hydrochloride
SMILES O=C(C1=C(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])([H])N([H])[H])C([H])=C2[H])SC(C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])/C4=N\N([H])C5=NC6=C([H])C([H])=C([H])C([H])=C6S5)=N1)O[H]

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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