Biological Activity
WIKI4 is a novel Tankyrase inhibitor with IC50 of 15 nM for TNKS2.
Targets
TNKS2 | ||||
15 nM |
In vitro | DMSO | 7 mg/mL heating (13.42 mM) | |
Water | <1 mg/mL (<1 mM) | ||
Ethanol | <1 mg/mL (<1 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.17 mL | 95.86 mL | 191.72 mL |
0.5 mM | 3.83 mL | 19.17 mL | 38.34 mL |
1 mM | 1.92 mL | 9.59 mL | 19.17 mL |
5 mM | 0.38 mL | 1.92 mL | 3.83 mL |
*The above data is based on the productmolecular weight 521.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A14283 |
---|---|
Actions | Inhibitor |
M. Wt | 521.59 |
Formula | C29H23N5O3S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 838818-26-1 |
Synonyms | WIKI-4 |
SMILES | COC1=CC=C(C=C1)N2C(=NN=C2SCCCN3C(=O)C4=CC=CC5=C4C(=CC=C5)C3=O)C6=CC=NC=C6 |
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