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WIZ degrader 5

WIZ Degrader

WIZ Degrader 5 is a selective degrader targeting the WIZ protein, facilitating efficient degradation with a maximum efficacy of 88.6% observed in 293T cells. This reagent is particularly valuable for investigating the biological mechanisms underlying sickle cell disease, enabling researchers to explore novel therapeutic approaches.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2879250-73-2
Applications	WIZ Degrader
Formula	C₂₁H₂₇N₃O₄
Molecular Weight	385.46
SMILES	O=C1N(C2C(NC(CC2)=O)=O)CC3=CC(O[C@H]4CN([C@H](CC4)C)CC)=CC=C31

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.