Fig. 1 · Structure

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WRN inhibitor 12

WRN Inhibitor

WRN Inhibitor 12 is a selective inhibitor of the Werner syndrome protein (WRN) helicase. This compound effectively modulates WRN's helicase activity, which plays a crucial role in DNA repair and maintenance. WRN Inhibitor 12 is valuable for research applications focused on aging, genomic instability, and the study of chromosomal dynamics.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3044040-29-8
Applications WRN Inhibitor
Formula C33H33ClF3N9O5
Molecular Weight 728.12
SMILES
CCC1=C(C(N2N=C(N=C2N1CC(NC3=CC=C(C=C3Cl)C(F)(F)F)=O)C4=CCOCC4)=O)N5C6CCC5CN(C6)C(C7=NC=NC(C)=C7O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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