Fig. 1 · Structure

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WRN inhibitor 13

WRN Helicase Inhibitor

WRN Inhibitor 13 is a selective inhibitor of the WRN helicase, exhibiting a pIC50 value in the range of 6-7. This compound is valuable for studies focused on DNA repair mechanisms, particularly in relation to cancer research and aging. WRN Inhibitor 13 aids in elucidating the role of WRN helicase in maintaining genomic stability and offers potential therapeutic avenues for WRN-related diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2923009-51-0
Applications WRN Helicase Inhibitor
Formula C16H20N2O5S
Molecular Weight 352.41
SMILES
OC1=C(C2CCCCC2)NC(C(C(N[C@H]3C=CS(=O)(C3)=O)=O)=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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