Fig. 1 · Structure

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WRN inhibitor 17

WRN Inhibitor

WRN Inhibitor 17 is a potent inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), specifically targeting its helicase domain activity. This small molecule demonstrates significant potential in research applications related to cancer, offering insights into the role of WRN in tumor biology and therapeutic strategies. Its ability to modulate WRN function makes it a valuable tool for studying DNA damage response and repair mechanisms in cancer cells.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3064599-40-9
Applications WRN Inhibitor
Formula C33H34F4N4O6S
Molecular Weight 690.70
SMILES
COC[C@H]1C[C@H]([C@@H]([C@H](C1)C2=CC=C(C=C2)N(S(=O)(C3=CC4=C(N(C(C)=N4)C)C=C3)=O)C)C(O)=O)C(NC5=C(C=C(C=C5)C(F)(F)F)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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