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WRN inhibitor 18

WRN Inhibitor

WRN Inhibitor 18 is a selective inhibitor of Werner syndrome protein (WRN) that disrupts its helicase activity, leading to impaired DNA repair processes. This compound exhibits in vivo anticancer activity, making it a valuable tool for research into cancer therapeutics and the mechanisms underlying genomic instability. Its application extends to studying the role of WRN in cellular processes, including replication stress and tumor progression.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3064599-42-1
Applications	WRN Inhibitor
Formula	C₃₅H₃₅F₆N₅O₅S
Molecular Weight	751.74
SMILES	O=S(C1=CC2=C(C=C1)N(C)C(C)=N2)(N(C)C3=CC=C([C@H]4C[C@@H](N5CCC(C5)(F)F)C[C@@H](C(NC6=CC=C(C(F)(F)F)C=C6F)=O)[C@@H]4C(O)=O)C=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.