Fig. 1 · Structure
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WRN inhibitor 3
WRN Inhibitor
WRN Inhibitor 3 is a potent inhibitor of the Werner Syndrome ATP-dependent helicase (WRN), which plays a crucial role in DNA replication and repair. This cyclic vinyl sulfone compound demonstrates significant biological activity in disrupting WRN's function, making it a valuable tool for cancer research. Its application extends to studying the mechanisms of DNA repair pathways and potential therapeutic strategies targeting WRN in various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2923009-48-5 |
| Applications | WRN Inhibitor |
| Formula | C20H20N2O5S |
| Molecular Weight | 400.45 |
| SMILES | O=C1NC(C(C=CC=C2)=C2OCC3CC3)=CC=C1C(N[C@H]4CS(=O)(C=C4)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.