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WRN inhibitor 7

WRN Inhibitor

WRN Inhibitor 7 is a selective inhibitor targeting the Werner helicase (WRN). It effectively inhibits both the helicase and ATPase activities of WRN, with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is valuable for research focused on microsatellite unstable (MSI) cancers, providing a tool for investigating the role of WRN in DNA repair and tumorigenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	444780-45-4
Applications	WRN Inhibitor
Formula	C₂₇H₂₃N₃O₆
Molecular Weight	485.49
SMILES	O=C(N/1)N(CC(NC2=CC=C(C)C=C2)=O)C(C1=C/C3=C(OCC4=CC(C(O)=O)=CC=C4)C=CC=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.