Fig. 1 · Structure
Documents & Downloads
WRN inhibitor 8
WRN Helicase Inhibitor
WRN Inhibitor 8 is a selective inhibitor of WRN helicase, exhibiting an IC50 value of 48 nM. This compound effectively impedes tumor cell proliferation and is valuable for research in cancer biology, particularly in studies focusing on mechanisms of tumor progression and the potential therapeutic avenues targeting WRN helicase.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3026502-95-1 |
| Applications | WRN Helicase Inhibitor |
| Formula | C22H23F2N3O4S |
| Molecular Weight | 463.50 |
| SMILES | CS(/C=C/[C@H](C1CC1)NC(C(C(OC2=CC=CC=C2)=N3)=CN=C3C(F)(C4CC4)F)=O)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.