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WYE-103914

α7 nAChR Agonist

WYE-103914 is a selective agonist of the α7 nicotinic acetylcholine receptor (nAChR), exhibiting EC50 values of 0.49 µM for rat and 0.57 µM for human receptors. This compound is known to enhance cognitive functions and memory in various experimental models. It is also utilized in research focusing on schizophrenia and can be administered alongside antipsychotic therapies to investigate potential synergistic effects.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1204607-09-9
Applications	α7 nAChR Agonist
Formula	C₂₁H₂₇FN₄O
Molecular Weight	370.46
SMILES	O=C(NC1=CC=C(C2=CC=C(F)C=C2)N=C1)NCCCCN3CCCCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.