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$0.00 Biological Activity
WZB117 is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 uM.
Targets
| GLUT1 | ||||
| 10μM |
| In vitro | DMSO | 64 mg/mL (173.76 mM) | |
| Water | Insoluble | ||
| Ethanol | 64 mg/mL (173.76 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.15 mL | 135.76 mL | 271.51 mL |
| 0.5 mM | 5.43 mL | 27.15 mL | 54.3 mL |
| 1 mM | 2.72 mL | 13.58 mL | 27.15 mL |
| 5 mM | 0.54 mL | 2.72 mL | 5.43 mL |
*The above data is based on the productmolecular weight 368.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15877 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1223397-11-2 |
| Formula | C20H13FO6 |
| M. Wt | 368.31 |
| Purity | >98% |
| Synonyms | WZB 117, WZB-117 |
| SMILES | C1=CC(=CC(=C1)O)C(=O)OC2=C(C(=CC=C2)F)OC(=O)C3=CC(=CC=C3)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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