Fig. 1 · Structure
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Xanthine oxidoreductase-IN-6
XOR Inhibitor
Xanthine oxidoreductase-IN-6 is a potent inhibitor of xanthine oxidoreductase (XOR), exhibiting an IC50 of 170 nM. By effectively blocking the final step in uric acid biosynthesis, this compound contributes to the reduction of serum uric acid levels. Additionally, Xanthine oxidoreductase-IN-6 has been shown to inhibit Cytochrome P450 3A4 (CYP3A4), making it a valuable tool for studying hyperuricemia and its related metabolic disorders. Researchers may utilize this compound to explore therapeutic strategies for conditions associated with elevated uric acid levels.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4329-78-6 |
| Applications | XOR Inhibitor |
| Formula | C12H9N5 |
| Molecular Weight | 223.24 |
| SMILES | C1(C2=CC=NC=C2)=NNC(C3=CC=NC=C3)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.