XAP044 is a highly selective antagonist of the metabotropic glutamate receptor subtype 7 (mGlu7), which serves as a key presynaptic modulator of neurotransmission in the central nervous system. It is characterized by significant brain permeability and has been shown to exhibit a broad range of anti-stress effects, as well as antidepressant and anxiolytic-like activity in rodent behavioral models. This compound is useful for research applications aimed at understanding mGlu7's role in neuropsychiatric disorders.
XAP044 is a highly selective antagonist of the metabotropic glutamate receptor subtype 7 (mGlu7), which serves as a key presynaptic modulator of neurotransmission in the central nervous system. It is characterized by significant brain permeability and has been shown to exhibit a broad range of anti-stress effects, as well as antidepressant and anxiolytic-like activity in rodent behavioral models. This compound is useful for research applications aimed at understanding mGlu7's role in neuropsychiatric disorders.
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