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XE 991 dihydrochloride

Catalog No.: A20032
Kv7 (KCNQ) channels blocker
XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 ?M, 0.71 ?M, 0.6 μM, and 0.98 ?M, respectively.
XE 991 dihydrochloride
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Product Name Price Stock Qty
XE 991 dihydrochloride 1mg
$320.00
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XE 991 dihydrochloride 5mg
$960.00
In stock
XE 991 dihydrochloride 10mg
$1,600.00
In stock
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Biological Activity
Discription XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 ?M, 0.71 ?M, 0.6 μM, and 0.98 ?M, respectively.
Product Information
Catalog Num A20032
Formula C26H22Cl2N2O
Molecular Weight 449.37
CAS Number 122955-13-9
SMILES O=C1C2=C(C=CC=C2)C(CC3=CC=NC=C3)(CC4=CC=NC=C4)C5=CC=CC=C15.Cl.Cl
Synonyms XE991, XE991
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Membrane Transporters-Ion Channels > Potassium Channels
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