Fig. 1 · Structure
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Xenin-8
Insulin Stimulator
Xenin-8 is a C-terminal octapeptide derived from the biologically active fragment of the neurotensin/xenopsin family peptide, Xenin. This compound functions as an insulin stimulator, enhancing basal insulin secretion and amplifying the insulin response to glucose in a dose-dependent manner, with an EC50 of 0.16 nM. Xenin-8 is applicable for research into metabolic disorders, diabetes, and the regulatory mechanisms of insulin secretion.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 117442-28-1 |
| Applications | Insulin Stimulator |
| Formula | C51H79N15O9 |
| Molecular Weight | 1046.27 |
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.