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Xenopus orexin A

Catalog No.: A62740
Orexin Receptor Activator
Xenopus orexin A acts as a potent agonist of the orexin receptor OX1R, functioning as a neuropeptide that binds to G-protein-coupled receptors. This endogenous ligand plays a critical role in modulating various physiological processes, including appetite regulation and arousal. Research applications of Xenopus orexin A include studying energy homeostasis, sleep-wake cycles, and potential implications in metabolic disorders.
Xenopus orexin A 254757-77-2 Orexin Receptor Activator
Grouped product items
Size Price Stock Qty
5mg
$350.00
In stock
10mg
$650.00
In stock
50mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXenopus orexin A acts as a potent agonist of the orexin receptor OX1R, functioning as a neuropeptide that binds to G-protein-coupled receptors. This endogenous ligand plays a critical role in modulating various physiological processes, including appetite regulation and arousal. Research applications of Xenopus orexin A include studying energy homeostasis, sleep-wake cycles, and potential implications in metabolic disorders.
Product Information
Catalog NumA62740
FormulaC139H230N46O42S4
Molecular Weight3345.86
CAS Number254757-77-2
SequenceAla-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Ile-Tyr-Asp-Ile-Leu-Arg-Gly-Thr-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys12)
Sequence shorteningAPDCCRQKTCSCRIYDILRGTGNHAAGILTL-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys12)
SMILESC(N[C@H](C(N[C@@H]1C(=O)N[C@@]2(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@](CSSC1)(C(=O)N[C@@H](CO)C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)[C@@H](C)O)=O)CC(C)C)=O)[C@H](CC)C)=O)=O)C)=O)C)=O)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)[C@H](CC)C)=O)CC(O)=O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CSSC2)[H])[H])[H])=O)CC(O)=O)(=O)[C@H]5N(C([C@H](C)N)=O)CCC5
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GPCR/G Protein > Orexin Receptors