Fig. 1 · Structure

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XIAP antagonist 1

XIAP Degrader

XIAP Antagonist 1 specifically targets XIAP (X-linked inhibitor of apoptosis protein) for degradation, activating the ubiquitin-proteasome pathway. This compound facilitates the efficient breakdown of XIAP, leading to the release of apoptotic factors and promoting programmed cell death. Its biological activity makes it valuable for research in cancer biology and therapeutic strategies aimed at overcoming apoptosis resistance.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 375835-04-4
Applications XIAP Degrader
Formula C23H25ClN4O3
Molecular Weight 440.92
SMILES
O=C(NC1=C(NC2=C1C=C(Cl)C=C2)C(OC)=O)CN(CC3)CCN3CC4=CC=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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