Fig. 1 · Structure
Documents & Downloads
XIE18-6
p18 Inhibitor
XIE18-6 is a potent inhibitor of the INK4C (p18) protein, which plays a critical role in cell cycle regulation. This compound demonstrates significant bioactivity in the expansion of hematopoietic stem cells (HSCs), exhibiting an effective dose (ED50) of 105.5 nM. XIE18-6 is valuable for research focused on stem cell biology, cancer research, and the development of regenerative medicine therapies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1286862-52-9 |
| Applications | p18 Inhibitor |
| Formula | C18H15NO6S |
| Molecular Weight | 373.38 |
| SMILES | O=S(C1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(C(O3)=C2)C(C)=CC3=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.