Fig. 1 · Structure
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XPW1
CDK9 Inhibitor
XPW1 is a potent and selective inhibitor of CDK9, a key regulator in transcriptional control linked to cancer progression. This compound exhibits significant anti-tumor activity against clear cell renal cell carcinoma (ccRCC) and demonstrates favorable toxicity profiles. Its unique mechanism of action makes it a valuable tool for research into CDK9's role in cancer biology and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2700286-66-2 |
| Applications | CDK9 Inhibitor |
| Formula | C36H39ClFN7O2 |
| Molecular Weight | 656.19 |
| SMILES | O=C(N[C@H]1CC[C@H](NC2=NC=C(Cl)C(C3=NC(NCC4=CC=CC(F)=C4)=CC=C3)=C2)CC1)C5=CC=C(NC(/C=C/CN(C)C)=O)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.