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Biological Activity
XRP44X is a Ras-Net (Elk-3) pathway inhibitor (IC50 = 10-20 nM). Indirectly inhibits Net phosphorylation upstream of Erk1/2 activation.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.26 mL | 131.28 mL | 262.56 mL |
| 0.5 mM | 5.25 mL | 26.26 mL | 52.51 mL |
| 1 mM | 2.63 mL | 13.13 mL | 26.26 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.25 mL |
*The above data is based on the productmolecular weight 380.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16049 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 729605-21-4 |
| Formula | C21H21ClN4O |
| M. Wt | 380.87 |
| Purity | >98% |
| Synonyms | XRP 44X |
| SMILES | ClC1=CC(N2CCN(C(C3=CC(C)=NN3C4=CC=CC=C4)=O)CC2)=CC=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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