Fig. 1 · Structure

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XV459

GPIIb/IIIa Antagonist

XV459 is a potent GPIIb/IIIa receptor antagonist that exhibits oral bioactivity. By binding to the GPIIb/IIIa receptors on platelets, XV459 effectively inhibits all agonist-induced platelet aggregation. This compound is shown to significantly prolong occlusion time, reduce thrombus weight, and maintain blood flow, making it a valuable tool in anti-thrombotic research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 170902-52-0
Applications GPIIb/IIIa Antagonist
Formula C20H27N5O6
Molecular Weight 433.46
SMILES
O=C([C@@H](NC(OCCCC)=O)CNC(C[C@H]1CC(C2=CC=C(C=C2)C(N)=N)=NO1)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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