Fig. 1 · Structure
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Y-20024 hydrochloride
D2 Receptor Antagonist
Y-20024 hydrochloride is a selective D2 receptor antagonist known for its ability to cross the blood-brain barrier. It effectively inhibits Apomorphine-induced symptoms associated with attention deficit hyperactivity disorder (ADHD) in murine models and also mitigates Apomorphine-induced vomiting in canine subjects. This compound demonstrates prolactin-promoting activity and is valuable for research into neurological disorders such as ADHD and emesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 124842-93-9 |
| Applications | D2 Receptor Antagonist |
| Formula | C19H30ClN3O4S |
| Molecular Weight | 431.98 |
| SMILES | O=C(C1=C(OC(C)C2)C2=CC(S(=O)(N)=O)=C1)NCC3N(CCCC)CCC3.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.